Synonyms:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate
辛酸七烷-9-基 8-(2-羥乙基)(8-壬氧基)-8-氧辛基)氨基酯
1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate
1-辛(xin)基壬基8-[(2-羥乙基)[8-(壬氧基)-8-氧辛(xin)基]氨基]辛(xin)酸酯

分子式: C44H87NO5
分子量: 710.17
Storage condition: 2 years -20°C Powder, 2 weeks 4°C in DMSO,6 months -80°C in DMSO

新型(xing)(xing)可(ke)電(dian)離氨(an)基脂(zhi)質(zhi)，用(yong)于形成納米脂(zhi)質(zhi)遞(di)送(song)系統LNPs，遞(di)送(song)mRNA核酸(suan)藥(yao)物（如新冠疫苗(miao)，基因藥(yao)物等）。可(ke)在嚙齒動物和靈長類動物模型(xing)(xing)中提供有效(xiao)的 mRNA 遞(di)送(song)，顯示出最佳的藥(yao)代動力學和無毒副作(zuo)用(yong)。